Phenotypes associated with this allele

• Allele Symbol: Rnf126^tm1.1Bcgen
• Allele Name: targeted mutation 1.1, Biocytogen
• Allele ID: MGI:7614508
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf126^tm1.1Bcgen/Rnf126^tm1.1Bcgen	FVB.B6(Cg)-Rnf126^tm1.1Bcgen	MGI:7705943

Genotype
MGI:7705943

hm1

• Allelic Composition: Rnf126^tm1.1Bcgen/Rnf126^tm1.1Bcgen
• Genetic Background: FVB.B6(Cg)-Rnf126^tm1.1Bcgen

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased mortality induced by ionizing radiation ( J:344817 )

• mice treated with irradiation at 2 months of age exhibit a shorter survival time than treated wild-type mice

prenatal lethality, incomplete penetrance ( J:344817 )

• partial embryonic lethality (time not specified), with fewer than the expected numbers of offspring obtained from heterozygous matings

homeostasis/metabolism

increased mortality induced by ionizing radiation ( J:344817 )

• mice treated with irradiation at 2 months of age exhibit a shorter survival time than treated wild-type mice

cellular

increased cellular sensitivity to ionizing radiation ( J:344817 )

• tissues show increased apoptosis on day 7 after irradiation exposure compared to wild-type mice