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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Trhr2tm1Gemc
targeted mutation 1, Marvin C Gershengorn
MGI:7614548
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Trhr2tm1Gemc/Trhr2tm1Gemc involves: 129S6/SvEvTac MGI:7614555


Genotype
MGI:7614555
hm1
Allelic
Composition		 Trhr2tm1Gemc/Trhr2tm1Gemc
Genetic
Background		 involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trhr2tm1Gemc mutation (0 available); any Trhr2 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal depression-related behavior ( J:345858 )
• females but not males show a significant increase in immobility time in a tail suspension test
decreased anxiety-related response ( J:345858 )
• increased feeding time and reduced latency to eat in a novelty-induced hypophagia test in females but not males indicating reduced anxiety




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory