Analysis Tools
homeostasis/metabolism
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• on a high fat diet, males and females gain slightly more weight over time
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• elevated serum ketones in response to overnight food withdrawal in females but not males
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• fasting serum cholesterol levels are increased in females but not males on a high fat diet
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• in the refeeding phase in females on a normal chow diet but not on a high fat diet
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• in the refeeding phase in females
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• in males and females on a high fat diet
• more pronounced in males
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• in males on a high fat diet
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behavior/neurological
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• reduced food intake in the refeeding phase in a fasting-refeeding cycle in females on a normal chow diet but not on a high fat diet
• show smaller meal size and shorter meal duration in the refeeding phase
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• modestly reduced in males but not females
• but no abnormalities are seen in gastrocnemius histology, fiber size, or weight
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• markedly reduced ambulatory activity in females during the dark cycle when on a normal chow diet but not on a high fat diet
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growth/size/body
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• in obese male mice switched back to a low fat diet loss of fat mass is reduced
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• on a high fat diet, males and females gain slightly more weight over time
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hematopoietic system
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• in females on a high fat diet
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• in females on a high fat diet
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• in males on a high fat diet
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• in males on a high fat diet
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• in males on a high fat diet
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adipose tissue
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• in obese male mice switched back to a low fat diet loss of fat mass is reduced
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• modest increase in the percent fat mass of the inguinal fat depot normalized to body weight in males on a high fat diet
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immune system
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• in males on a high fat diet
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• in males on a high fat diet
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