All Phenotypes Gcc2<em1Cya> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gcc2^em1Cya
endonuclease-mediated mutation 1, Cyagen Biosciences
MGI:7620191

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gcc2^em1Cya/Gcc2^em1Cya	C57BL/6J-Gcc2^em1Cya	MGI:7621854

Allelic Composition	Gcc2^em1Cya/Gcc2^em1Cya
Genetic Background	C57BL/6J-Gcc2^em1Cya

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gcc2^em1Cya mutation (0 available); any Gcc2 mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased autoantibody level ( J:346915 )

• increased IgM autoantibodies against a range of antigens commonly associated with lupus and other autoimmune diseases at 6 months of age

• however, IgG autoantibodies and serum cytokines are similar to controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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