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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fars2em1Chenk
endonuclease-mediated mutation 1, Kun Chen
MGI:7621486
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fars2em1Chenk/Fars2em1Chenk involves: C57BL/6J MGI:7624360


Genotype
MGI:7624360
hm1
Allelic
Composition		 Fars2em1Chenk/Fars2em1Chenk
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fars2em1Chenk mutation (0 available); any Fars2 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:339244 )
• at E7.5-E8.0 embryos appear to have arrested at the early streak stage and extraembryonic tissues have begun to disintegrate

embryo
abnormal ectoderm development ( J:339244 )
• expression analysis indicates failure of ectoderm development at E7.5-8.0
embryonic growth arrest ( J:339244 )
• arrest at the early streak stage




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory