About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fars2em2Chenk
endonuclease-mediated mutation 2, Kun Chen
MGI:7621487
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fars2em2Chenk/Fars2em2Chenk involves: C57BL/6J MGI:7624362


Genotype
MGI:7624362
hm1
Allelic
Composition		 Fars2em2Chenk/Fars2em2Chenk
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fars2em2Chenk mutation (0 available); any Fars2 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:339244 )
• at E7.5-E8.0 embryos appear to have arrested at the early streak stage and extraembryonic tissues have begun to disintegrate

embryo
abnormal ectoderm development ( J:339244 )
• expression analysis indicates failure of ectoderm development at E7.5-8.0
embryonic growth arrest ( J:339244 )
• arrest at the early streak stage




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory