Analysis Tools
immune system
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• frequencies of double negative, double positive, and single positive T cells in the thymus are similar to controls
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• increase in spleen weight and cell numbers in aged mice
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• increase in frequencies of B cells in mice at 8 and 12 weeks of age in the spleen
• increase in IgG1+ B cells at 8 and 21 days after LCMV infection
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• increase in germinal center B cells in spleens and lymph nodes in aged mice
• increased after immunization compared to similarly immunized wild-type controls
• increased at 8 and 21 days after LCMV infection
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• increase in the frequencies of effector CD4+ T cells in the spleen
• however, numbers of CD8+ T cells and other T helper cell subsets are unchanged
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• increase in spleens and lymph nodes in aged mice
• increase in relative and absolute numbers 7 days after immunization compared to similarly immunized wild-type controls
• following infection with LCMV increase in the number of virus-specific gp66 tetramer-positive CD4+ T cell
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• strong increase in total splenocyte number
• increase in splenocyte numbers at 8 days following lymphocytic choriomeningitis virus infection with significant expansion of CD4+ T helper cells compared to similarly infected wild-type mice
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• increase in splenocyte numbers at 8 days following lymphocytic choriomeningitis virus (LCMV) infection with significant expansion of CD4+ T helper cells compared to similarly infected wild-type mice
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growth/size/body
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• increase in spleen weight and cell numbers in aged mice
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hematopoietic system
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• increase in spleen weight and cell numbers in aged mice
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• increase in frequencies of B cells in mice at 8 and 12 weeks of age in the spleen
• increase in IgG1+ B cells at 8 and 21 days after LCMV infection
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• increase in germinal center B cells in spleens and lymph nodes in aged mice
• increased after immunization compared to similarly immunized wild-type controls
• increased at 8 and 21 days after LCMV infection
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• increase in the frequencies of effector CD4+ T cells in the spleen
• however, numbers of CD8+ T cells and other T helper cell subsets are unchanged
|
|
• increase in spleens and lymph nodes in aged mice
• increase in relative and absolute numbers 7 days after immunization compared to similarly immunized wild-type controls
• following infection with LCMV increase in the number of virus-specific gp66 tetramer-positive CD4+ T cell
|
|
• strong increase in total splenocyte number
• increase in splenocyte numbers at 8 days following lymphocytic choriomeningitis virus infection with significant expansion of CD4+ T helper cells compared to similarly infected wild-type mice
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