All Phenotypes Clec10a<m1> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Clec10a^m1
mutation 1
MGI:7624304

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Clec10a^m1/Clec10a^m1	NC/Nga	MGI:7624338

Allelic Composition	Clec10a^m1/Clec10a^m1
Genetic Background	NC/Nga

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clec10a^m1 mutation (0 available); any Clec10a mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

integument phenotype ( J:283174 )

N	• normal eosinophil cell numbers in skin after exposure to house dust mites (HDMs)

dermatitis ( J:283174 )

• hypersensitivity to house dust mite (HDM)-induced skin inflammation (erythema, dryness, increased epidermal thickness)

immune system

immune system phenotype ( J:283174 )

N	• normal serum IgE levels after exposure to house dust mites (HDMs) • normal eosinophil cell numbers in skin after exposure to house dust mites (HDMs)

increased neutrophil cell number ( J:283174 )

• increased neutrophil infiltration in skin 6 days after exposure to house dust mites (HDMs)

dermatitis ( J:283174 )

• hypersensitivity to house dust mite (HDM)-induced skin inflammation (erythema, dryness, increased epidermal thickness)

hematopoietic system

increased neutrophil cell number ( J:283174 )

• increased neutrophil infiltration in skin 6 days after exposure to house dust mites (HDMs)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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