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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Clec10am1
mutation 1
MGI:7624304
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Clec10am1/Clec10am1 NC/Nga MGI:7624338


Genotype
MGI:7624338
hm1
Allelic
Composition		 Clec10am1/Clec10am1
Genetic
Background		 NC/Nga
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clec10am1 mutation (0 available); any Clec10a mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
integument phenotype ( J:283174 )
N
• normal eosinophil cell numbers in skin after exposure to house dust mites (HDMs)
dermatitis ( J:283174 )
• hypersensitivity to house dust mite (HDM)-induced skin inflammation (erythema, dryness, increased epidermal thickness)

immune system
immune system phenotype ( J:283174 )
N
• normal serum IgE levels after exposure to house dust mites (HDMs)
• normal eosinophil cell numbers in skin after exposure to house dust mites (HDMs)
increased neutrophil cell number ( J:283174 )
• increased neutrophil infiltration in skin 6 days after exposure to house dust mites (HDMs)
dermatitis ( J:283174 )
• hypersensitivity to house dust mite (HDM)-induced skin inflammation (erythema, dryness, increased epidermal thickness)

hematopoietic system
increased neutrophil cell number ( J:283174 )
• increased neutrophil infiltration in skin 6 days after exposure to house dust mites (HDMs)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory