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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tfap2bem1Sleep
endonuclease-mediated mutation 1, Yu Hayashi
MGI:7627101
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tfap2bem1Sleep/Tfap2bem1Sleep C57BL/6J-Tfap2bem1Sleep MGI:7627363
ht2
 		Tfap2bem1Sleep/Tfap2b+ C57BL/6J-Tfap2bem1Sleep MGI:7627365


Genotype
MGI:7627363
hm1
Allelic
Composition		 Tfap2bem1Sleep/Tfap2bem1Sleep
Genetic
Background		 C57BL/6J-Tfap2bem1Sleep
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tfap2bem1Sleep mutation (0 available); any Tfap2b mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:297685 )
N
• viable

mortality/aging
mortality/aging ( J:297685 )
N
• viable




Genotype
MGI:7627365
ht2
Allelic
Composition		 Tfap2bem1Sleep/Tfap2b+
Genetic
Background		 C57BL/6J-Tfap2bem1Sleep
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tfap2bem1Sleep mutation (0 available); any Tfap2b mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal circadian sleep/wake cycle ( J:297685 )
• increased time spent in wakefulness during dark phase
abnormal non-rapid eye movement sleep pattern ( J:297685 )
• reduced total time spent in NREM sleep
• reduced number of NREM sleep episodes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory