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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(CAG-cat,-Tcf25)1Xdgz
transgene insertion 1, Xiao-Dong Zhang
MGI:7628235
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
Tg(CAG-cat,-Tcf25)1Xdgz/0 		involves: C57BL/6J * FVB/N MGI:7639760


Genotype
MGI:7639760
cn1
Allelic
Composition		 A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
Tg(CAG-cat,-Tcf25)1Xdgz/0
Genetic
Background		 involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A1cfTg(Myh6-cre/Esr1*)1Jmk mutation (5 available); any A1cf mutation (39 available)
Tg(CAG-cat,-Tcf25)1Xdgz mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased response of heart to induced stress ( J:317382 )
• cardiac hypertrophy induced by aortic banding is blunted with a smaller increase in heart weight , improved cardiac performance, less pronounced hypertrophic morphological changes, and reduced myocardial fibrosis

homeostasis/metabolism
decreased response of heart to induced stress ( J:317382 )
• cardiac hypertrophy induced by aortic banding is blunted with a smaller increase in heart weight , improved cardiac performance, less pronounced hypertrophic morphological changes, and reduced myocardial fibrosis




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory