Analysis Tools
craniofacial
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• narrower pulp volume in molars
• decrease in pulp cell populations at 6 months of age
• round-shaped cells are trapped in the lacunae-like spaces in the pathological dentin structure
• increase in the number of cells with nuclear deformations
• extensive obliteration of pulp space due to accelerated tertiary dentin deposition and sparse cell distribution at 12 months of age
• pulp at 6 months of age is similar to that of wild-type mice at 23 months of age
• increased accumulation of markers of DNA damage in dental pulp cells in molars at 6 months of age
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• radicular pulp is partly obliterated with abnormal bone-like tissue at 6 months of age
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• narrower pulp volume in molars
• decreased coronal dentin thickness in maxillary and mandibular first molars at 6 months of age
• however, no changes in mandibular incisor morphology are detected at 6 and 12 months of age
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• decreased coronal dentin thickness in maxillary and mandibular first molars at 6 months of age
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• disruption of odontoblast alignment at 6 months of age
• multiple cellular extensions stemming from a single cell body are seen
• at 12 months of age the typical palisade layer of odontoblasts is completely collapsed
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cellular
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• increased senescence of cells in the dental pulp with in vitro analysis indicating these are odontoblasts
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growth/size/body
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• narrower pulp volume in molars
• decrease in pulp cell populations at 6 months of age
• round-shaped cells are trapped in the lacunae-like spaces in the pathological dentin structure
• increase in the number of cells with nuclear deformations
• extensive obliteration of pulp space due to accelerated tertiary dentin deposition and sparse cell distribution at 12 months of age
• pulp at 6 months of age is similar to that of wild-type mice at 23 months of age
• increased accumulation of markers of DNA damage in dental pulp cells in molars at 6 months of age
|
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• radicular pulp is partly obliterated with abnormal bone-like tissue at 6 months of age
|
|
• narrower pulp volume in molars
• decreased coronal dentin thickness in maxillary and mandibular first molars at 6 months of age
• however, no changes in mandibular incisor morphology are detected at 6 and 12 months of age
|
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• decreased coronal dentin thickness in maxillary and mandibular first molars at 6 months of age
|
|
• disruption of odontoblast alignment at 6 months of age
• multiple cellular extensions stemming from a single cell body are seen
• at 12 months of age the typical palisade layer of odontoblasts is completely collapsed
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skeleton
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• narrower pulp volume in molars
• decrease in pulp cell populations at 6 months of age
• round-shaped cells are trapped in the lacunae-like spaces in the pathological dentin structure
• increase in the number of cells with nuclear deformations
• extensive obliteration of pulp space due to accelerated tertiary dentin deposition and sparse cell distribution at 12 months of age
• pulp at 6 months of age is similar to that of wild-type mice at 23 months of age
• increased accumulation of markers of DNA damage in dental pulp cells in molars at 6 months of age
|
|
• radicular pulp is partly obliterated with abnormal bone-like tissue at 6 months of age
|
|
• narrower pulp volume in molars
• decreased coronal dentin thickness in maxillary and mandibular first molars at 6 months of age
• however, no changes in mandibular incisor morphology are detected at 6 and 12 months of age
|
|
• decreased coronal dentin thickness in maxillary and mandibular first molars at 6 months of age
|
|
• disruption of odontoblast alignment at 6 months of age
• multiple cellular extensions stemming from a single cell body are seen
• at 12 months of age the typical palisade layer of odontoblasts is completely collapsed
|
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• increased apoptosis in the dental pulp
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