Phenotypes associated with this allele

• Allele Symbol: Firrm^em1.1Gpt
• Allele Name: endonuclease-mediated mutation 1.1, GemPharmatech
• Allele ID: MGI:7639967
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Firrm^em1.1Gpt/Firrm^em1.1Gpt	involves: C57BL/6JGpt	MGI:7641563

Genotype
MGI:7641563

hm1

• Allelic Composition: Firrm^em1.1Gpt/Firrm^em1.1Gpt
• Genetic Background: involves: C57BL/6JGpt

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:344887 )

• no homozygotes are recovered from heterozygous intercrosses, with about 25% deciduae found degenerated at E10.5 or E13.5

embryo

embryonic growth arrest ( J:344887 )

• at E10.5, four of 22 deciduae from heterozygous intercrosses appear smaller with placentas and sometimes remaining gastrulating embryos, suggesting that embryos can develop past E6.5

• at E13.5, nine of 30 deciduae are degenerated