Phenotypes associated with this allele

• Allele Symbol: Xaf1^em1Gaod
• Allele Name: endonuclease-mediated mutation 1, Daming Gao
• Allele ID: MGI:7645252
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Xaf1^em1Gaod/Xaf1^em1Gaod	involves: C57BL/6	MGI:7645254

Genotype
MGI:7645254

hm1

• Allelic Composition: Xaf1^em1Gaod/Xaf1^em1Gaod
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased susceptibility to diet-induced obesity ( J:338549 )

• gain less weight and have less fat composition on a high fat diet

decreased circulating glucose level ( J:338549 )

• on a high fat diet

decreased circulating insulin level ( J:338549 )

• on a high fat diet

decreased energy expenditure ( J:338549 )

• generate slightly less heat on a normal chow diet

• significantly less heat generation on a high fat diet

increased oxygen consumption ( J:338549 )

• on a high fat diet

improved glucose tolerance ( J:338549 )

• on a normal chow or high fat diet

increased insulin sensitivity ( J:338549 )

• on a normal chow or high fat diet

growth/size/body

decreased susceptibility to diet-induced obesity ( J:338549 )

• gain less weight and have less fat composition on a high fat diet