About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(CAG-RND2)1Jya
transgene insertion 1, Junji Yamauchi
MGI:7645346
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Tg(CAG-RND2)1Jya/0
Tg(Mbp-cre)9Gvn/0
involves: C57BL/6 * C57BL/6J * DBA/2 * FVB/N MGI:7645366


Genotype
MGI:7645366
cn1
Allelic
Composition
Tg(CAG-RND2)1Jya/0
Tg(Mbp-cre)9Gvn/0
Genetic
Background
involves: C57BL/6 * C57BL/6J * DBA/2 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CAG-RND2)1Jya mutation (0 available)
Tg(Mbp-cre)9Gvn mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• myelin sheath thickness is decreased in 28-day-old mice, with increased average g-ratios
• myelin sheath thickness is increased in 14-day old mice, with reduced average g-ratios
• corpus callosum shows increased myelin thickness in 14-day-old mice and decreased myelin thickness in 28-day-old mice
• expression levels of the myelin marker proteins MBP and CNPase are increased in 14-day-old mice but are decreased in brain tissues at P28





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
08/02/2024
MGI 6.24
The Jackson Laboratory