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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ube4bem1Bcgen
endonuclease-mediated mutation 1, Biocytogen LLC
MGI:7647232
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Tg(Nes-cre)1Kln/0
Ube4bem1Bcgen/Ube4bem1Bcgen
involves: C57BL/6N * SJL MGI:7657714


Genotype
MGI:7657714
cn1
Allelic
Composition
Tg(Nes-cre)1Kln/0
Ube4bem1Bcgen/Ube4bem1Bcgen
Genetic
Background
involves: C57BL/6N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Nes-cre)1Kln mutation (4 available)
Ube4bem1Bcgen mutation (0 available); any Ube4b mutation (75 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• half of mice do not survive beyond the first week after birth
• mice suffer sudden deaths with few mice reaching adulthood
• mice often died the day after epileptic episode

nervous system
• with tail curling, back hunching, rhythmic twitching and rolling behaviors
• reduced cell density at P0
• however, brain size and cortex thickness are normal
• mild disorganization in the cerebral cortex

behavior/neurological
• with tail curling, back hunching, rhythmic twitching and rolling behaviors

growth/size/body

cellular





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory