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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mylk4em1Yima
endonuclease-mediated mutation 1, Yuuki Imai
MGI:7647256
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mylk4em1Yima/Mylk4em1Yima Not Specified MGI:7647263


Genotype
MGI:7647263
hm1
Allelic
Composition		 Mylk4em1Yima/Mylk4em1Yima
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mylk4em1Yima mutation (0 available); any Mylk4 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:316008 )
• body weight is slightly decreased
• however, weight of the gastrocnemius muscle is not different

muscle
abnormal muscle physiology ( J:316008 )
• maximum isometric torque normalized by the whole weight of the plantar flexor muscles is decreased
• passive stiffness of tibialis anterior muscle fibers is decreased
• however, post-tetanic potentiation is unchanged in plantar flexor muscles and calcium-activated force in anterior muscle fibers is unchanged




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory