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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Trim66em2Emr
endonuclease-mediated mutation 2, EMBL Rome
MGI:7657543
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Trim66em2Emr/Trim66em2Emr C57BL/6JCrl-Trim66em2Emr MGI:7657548


Genotype
MGI:7657548
hm1
Allelic
Composition		 Trim66em2Emr/Trim66em2Emr
Genetic
Background		 C57BL/6JCrl-Trim66em2Emr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trim66em2Emr mutation (0 available); any Trim66 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
paternal effect ( J:349240 )
• pups sired by homozygous males mated to wild-type females are heavier than wild-type pups at birth while no difference in weight for pups born from homozygous mothers bred with wild-type males is seen, indicating a paternal effect on intrauterine overgrowth of offspring
• however, the size of litters produced by homozygous males mated with wild-type females is normal

reproductive system
reproductive system phenotype ( J:349240 )
N
• males exhibit normal testis weight and morphology, and normal sperm morphology, sperm numbers, sperm motility, and sperm fertilization efficiency in IVF




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory