normal phenotype
• mice develop with no apparent abnormalities and show normal aging, no phenotypic differences in blood, thymus, spleen, bone marrow, and gut, or in proliferation of splenic T cells in response to CD3/CD28, in differentiation of memory T cells, and show normal phenotype and B cell counts in the spleen, normal proportions of proliferating CD19+CD95+GL-7+ B cells in Peyers patches, and normal proliferation of splenic B cells stimulated with LPS plus IL-4
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