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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		rd25
retinal degeneration 25
MGI:7660543
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		rd25/rd25 B6.Cg-rd25/BocJ MGI:7660551


Genotype
MGI:7660551
hm1
Allelic
Composition		 rd25/rd25
Genetic
Background		 B6.Cg-rd25/BocJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
rd25 mutation (2 available); any rd25 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

vision/eye
retina degeneration ( J:349874 )
• Although homozygotes have a normal retina at 3 months of age they begin to display retinal degeneration by 5 months of age and have 30-40% photoreceptor loss at 10 months of age
abnormal rod electrophysiology ( J:349874 )
• homozygotes have normal rod ERG responses at 3 months of age, but diminished at 5 and 10 months of age; the cone ERG responses are not much changed in this time frame

nervous system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory