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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Or51e2tm3.1Mom
targeted mutation 3.1, Peter Mobaerts
MGI:7662976
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Or51e2tm3.1Mom/Or51e2tm3.1Mom
Thtm1(cre)Te/? 		involves: 129X1/SvJ * C57BL/6 MGI:7663959


Genotype
MGI:7663959
cn1
Allelic
Composition		 Or51e2tm3.1Mom/Or51e2tm3.1Mom
Thtm1(cre)Te/?
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or51e2tm3.1Mom mutation (1 available); any Or51e2 mutation (21 available)
Thtm1(cre)Te mutation (1 available); any Th mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal type I cell of carotid body physiology ( J:350385 )
• these mice have normal hypoxic ventilatory response, but glomus cells have decreased quantal dopamine content, decreased secretory activity in response to hypoxia or hypoglycemia, decreased mean charge per exocytotic vessel, and altered cytosolic calcium dynamics.

nervous system
abnormal type I cell of carotid body physiology ( J:350385 )
• these mice have normal hypoxic ventilatory response, but glomus cells have decreased quantal dopamine content, decreased secretory activity in response to hypoxia or hypoglycemia, decreased mean charge per exocytotic vessel, and altered cytosolic calcium dynamics.




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory