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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Garin4em1Osb
endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI:7666153
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Garin4em1Osb/Garin4em1Osb involves: C57BL/6 * DBA/2 MGI:7666374


Genotype
MGI:7666374
hm1
Allelic
Composition
Garin4em1Osb/Garin4em1Osb
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Garin4em1Osb mutation (0 available); any Garin4 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• 92.4% of sperm heads exhibit bluntness in the hook regions (shortened sperm hooks)
• about 33.1% of spermatozoa heads exhibit one or multiple vacuoles
• however, the acrosome appears normal
• although males are fertile, zona pellucida penetration ability is reduced in in vitro fertilization

cellular
• 92.4% of sperm heads exhibit bluntness in the hook regions (shortened sperm hooks)
• about 33.1% of spermatozoa heads exhibit one or multiple vacuoles
• however, the acrosome appears normal





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory