About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Garin4em1Osb
endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI:7666153
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Garin4em1Osb/Garin4em1Osb involves: C57BL/6 * DBA/2 MGI:7666374


Genotype
MGI:7666374
hm1
Allelic
Composition
Garin4em1Osb/Garin4em1Osb
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Garin4em1Osb mutation (0 available); any Garin4 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• 92.4% of sperm heads exhibit bluntness in the hook regions (shortened sperm hooks)
• about 33.1% of spermatozoa heads exhibit one or multiple vacuoles
• however, the acrosome appears normal
• although males are fertile, zona pellucida penetration ability is reduced in in vitro fertilization

cellular
• 92.4% of sperm heads exhibit bluntness in the hook regions (shortened sperm hooks)
• about 33.1% of spermatozoa heads exhibit one or multiple vacuoles
• however, the acrosome appears normal





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory