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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Styxl1em2Xjg
endonuclease-mediated mutation 2, Xuejiang Guo
MGI:7703729
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Styxl1em2Xjg/Styxl1em2Xjg involves: C57BL/6J MGI:7703730


Genotype
MGI:7703730
hm1
Allelic
Composition		 Styxl1em2Xjg/Styxl1em2Xjg
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Styxl1em2Xjg mutation (0 available); any Styxl1 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:351148 )
N
• testes to body weight ratio is similar to controls
oligozoospermia ( J:351148 )
• extrememly reduced numbers in the cauda epididymis
teratozoospermia ( J:351148 )
• sperm from the cauda epididymis show severe morphological defects including abnormal heads and bent or coiled tails
abnormal sperm nucleus morphology ( J:351148 )
• nuclear abnormalities are seen starting at step 10 in elongating spermatids
male infertility ( J:351148 )
• males are completely infertile

cellular
oligozoospermia ( J:351148 )
• extrememly reduced numbers in the cauda epididymis
teratozoospermia ( J:351148 )
• sperm from the cauda epididymis show severe morphological defects including abnormal heads and bent or coiled tails
abnormal sperm nucleus morphology ( J:351148 )
• nuclear abnormalities are seen starting at step 10 in elongating spermatids




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/24/2024
MGI 6.24 		The Jackson Laboratory