Phenotypes associated with this allele

• Allele Symbol: Slc17a3^em1Araka
• Allele Name: endonuclease-mediated mutation 1, Hiroshi Arakawa
• Allele ID: MGI:7704013
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc17a3^em1Araka/Slc17a3^em1Araka	C57BL/6J-Slc17a3^em1Araka	MGI:7704018

Genotype
MGI:7704018

hm1

• Allelic Composition: Slc17a3^em1Araka/Slc17a3^em1Araka
• Genetic Background: C57BL/6J-Slc17a3^em1Araka

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal blood homeostasis ( J:351593 )

• serum levels of 11 endogenous metabolites, including hypotaurine, serotonin, cytidine, ribulose 5-phosphate, cysteine S-sulfate, uric acid, hypoxanthine and 3-indoxyl sulfate are increased by more than 2-fold

• serum levels of 6-phosphogluconate and 2,3-diphophoglycerate are decreased by more than 2-fold

increased blood uric acid level ( J:351593 )

• serum levels of uric acid are increased by more than 2-fold

increased circulating hypoxanthine level ( J:351593 )

• serum levels of hypoxanthine are increased by more than 2-fold

increased serotonin level ( J:351593 )

• serum levels of serotonin are increased by more than 2-fold

abnormal urine homeostasis ( J:351593 )

• urine levels of 11 endogenous metabolites, including 2-oxobutyrate and lactic acid are increased and levels of 17 endogenous metabolites including spermine and uric acid are decreased

decreased urine uric acid level ( J:351593 )

renal/urinary system

abnormal urine homeostasis ( J:351593 )

• urine levels of 11 endogenous metabolites, including 2-oxobutyrate and lactic acid are increased and levels of 17 endogenous metabolites including spermine and uric acid are decreased

decreased urine uric acid level ( J:351593 )