Phenotypes associated with this allele

• Allele Symbol: Kif18a^tm1.1Lgr
• Allele Name: targeted mutation 1.1, Laura Reinholdt
• Allele ID: MGI:7705503
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Kif18a^tm1.1Lgr/Kif18a^tm1.1Lgr Tg(Zp3-cre)93Knw/0	Not Specified	MGI:7854970

Genotype
MGI:7854970

cn1

• Allelic Composition: Kif18a^tm1.1Lgr/Kif18a^tm1.1Lgr; Tg(Zp3-cre)93Knw/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal female meiosis ( J:352185 )

♀ • This oocyte-specific loss results in increased frequency of misaligned chromosomes despite normal spindle length, inter-kinetochore distance, germinal vesicle breakdown, extrusion of the first polar body, and normal level of aneuploidy, with no spindle assembly checkpoint cell cycle arrest

abnormal meiotic configurations ( J:352185 )

♀

meiotic nondisjunction ( J:352185 )

♀

reproductive system

abnormal female meiosis ( J:352185 )

♀ • This oocyte-specific loss results in increased frequency of misaligned chromosomes despite normal spindle length, inter-kinetochore distance, germinal vesicle breakdown, extrusion of the first polar body, and normal level of aneuploidy, with no spindle assembly checkpoint cell cycle arrest

abnormal meiotic configurations ( J:352185 )

♀

meiotic nondisjunction ( J:352185 )

♀