Phenotypes associated with this allele

• Allele Symbol: Rr504^em3Takas
• Allele Name: endonuclease-mediated mutation 3, Shuji Takada
• Allele ID: MGI:7707823
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr504^em3Takas/Rr504^em3Takas	C57BL/6J-Rr504^em3Takas	MGI:7787120
ht2	Rr504^em1Takas/Rr504^em3Takas	involves: C57BL/6 * C57BL/6J * DBA/2	MGI:7787127

Genotype
MGI:7787120

hm1

• Allelic Composition: Rr504^em3Takas/Rr504^em3Takas
• Genetic Background: C57BL/6J-Rr504^em3Takas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryo phenotype ( J:334329 )

N • mice born at normal Mendelian ratios

endocrine/exocrine glands

abnormal testis interstitial tissue morphology ( J:334329 )

♂ • increased interstitial space among seminiferous tubules

increased testis weight ( J:334329 )

♂ • increased testis weight/body weight ratio

reproductive system

reproductive system phenotype ( J:334329 , J:334329 )

N • genitalia and gonads conform with genetic sex (J:334329)

♂N • normal anogenital distance/body weight (AGD/BW) ratio (J:334329)

♂N • normal seminiferous tubules with normal spermatogenesis (J:334329)

♂N • normal number of Leydig cells in fetal gonads (J:334329)

abnormal testis interstitial tissue morphology ( J:334329 )

♂ • increased interstitial space among seminiferous tubules

increased testis weight ( J:334329 )

♂ • increased testis weight/body weight ratio

Genotype
MGI:7787127

ht2

• Allelic Composition: Rr504^em1Takas/Rr504^em3Takas
• Genetic Background: involves: C57BL/6 * C57BL/6J * DBA/2

endocrine/exocrine glands

abnormal testis interstitial tissue morphology ( J:334329 )

♂ • increased interstitial space among seminiferous tubules

reproductive system

reproductive system phenotype ( J:334329 )

♂N • normal male external genitalia and internal gonads

♂N • normal spermatogenesis

abnormal testis interstitial tissue morphology ( J:334329 )

♂ • increased interstitial space among seminiferous tubules