Phenotypes associated with this allele

• Allele Symbol: Ubl7^em1Fanm
• Allele Name: endonuclease-mediated mutation 1, Min Fang
• Allele ID: MGI:7710910
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ubl7^em1Fanm/Ubl7^em1Fanm	involves: C57BL/6J	MGI:7710911

Genotype
MGI:7710911

hm1

• Allelic Composition: Ubl7^em1Fanm/Ubl7^em1Fanm
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased susceptibility to Riboviria infection induced morbidity/mortality ( J:349835 )

♂ • following vesicular stomatitis virus infection

increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality ( J:349835 )

♂ • following influenza A PR8 infection

growth/size/body

increased susceptibility to weight loss ( J:349835 )

♂ • increased weight loss following influenza A PR8 or vesicular stomatitis virus infection

immune system

increased susceptibility to Riboviria infection ( J:349835 )

♂ • increased weight loss and more severe lung lesions following vesicular stomatitis virus infection

increased susceptibility to Riboviria infection induced morbidity/mortality ( J:349835 )

♂ • following vesicular stomatitis virus infection

increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality ( J:349835 )

♂ • following influenza A PR8 infection

increased susceptibility to Orthomyxoviridae infection ( J:349835 )

♂ • increased weight loss and more severe lung lesions following influenza A PR8 infection

♂ • reduced transcript levels of cytokines and interferon-stimulated genes following influenza A PR8 infection