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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mir582em1Minz
endonuclease-mediated mutation 1, Min-Hua Zheng
MGI:7712843
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mir582em1Minz/Mir582em1Minz involves: C57BL/6 MGI:7712849


Genotype
MGI:7712849
hm1
Allelic
Composition
Mir582em1Minz/Mir582em1Minz
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir582em1Minz mutation (0 available); any Mir582 mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• the number of neural stem cells (type-B cells) and transient amplifying progenitors (type-C cells) in the subventricular zone are reduced in 8-week-old mice, while the number of DCX+ neuroblasts (type-A cells) are increased, indicating enhanced neurogenesis
• the number of Ki67+ cells in the subventricular zone is increased
• however, no difference in the number of CD24+ ependymal cells
• the number of neural stem cells in the subventricular zone region is decreased
• number of neural DCX+ neuroblasts is increased in the subventricular zone of 8-week-old mice
• stemness of neural stem cells is decreased in the subventricular zone





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory