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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gsaptm1.2Pggd
targeted mutation 1.2, Paul Greengard
MGI:7713179
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Gsaptm1.2Pggd/Gsaptm1.2Pggd
Zbtb20Tg(PDGFB-APPSwInd)20Lms/0 		involves: C57BL/6 * C57BL/6J * C57BL/6N * DBA/2 MGI:7713180


Genotype
MGI:7713180
cx1
Allelic
Composition		 Gsaptm1.2Pggd/Gsaptm1.2Pggd
Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
Genetic
Background		 involves: C57BL/6 * C57BL/6J * C57BL/6N * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gsaptm1.2Pggd mutation (0 available); any Gsap mutation (69 available)
Zbtb20Tg(PDGFB-APPSwInd)20Lms mutation (1 available); any Zbtb20 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:331150 )
N
• during the choice phase of the novel object recognition test, mice spend more time with the novel object and preference index shows that mice have greater preference toward the novel object indicating restoration of the recognition memory deficits seen in Zbtb20Tg(PDGFB-APPSwInd)20Lms/0 mice

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:331150 )
N
• hippocampal tissues show lower amyloid beta 40 and amyloid beta 42 levels than in Zbtb20Tg(PDGFB-APPSwInd)20Lms/0 mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory