All Phenotypes Gsap<tm1.2Pggd> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gsap^tm1.2Pggd
targeted mutation 1.2, Paul Greengard
MGI:7713179

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Gsap^tm1.2Pggd/Gsap^tm1.2Pggd Zbtb20^{Tg(PDGFB-APPSwInd)20Lms}/0	involves: C57BL/6 * C57BL/6J * C57BL/6N * DBA/2	MGI:7713180

Allelic Composition	Gsap^tm1.2Pggd/Gsap^tm1.2Pggd Zbtb20^{Tg(PDGFB-APPSwInd)20Lms}/0
Genetic Background	involves: C57BL/6 * C57BL/6J * C57BL/6N * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gsap^tm1.2Pggd mutation (0 available); any Gsap mutation (69 available)
Zbtb20^{Tg(PDGFB-APPSwInd)20Lms} mutation (1 available); any Zbtb20 mutation (58 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:331150 )

N	• during the choice phase of the novel object recognition test, mice spend more time with the novel object and preference index shows that mice have greater preference toward the novel object indicating restoration of the recognition memory deficits seen in Zbtb20^{Tg(PDGFB-APPSwInd)20Lms}/0 mice

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:331150 )

N	• hippocampal tissues show lower amyloid beta 40 and amyloid beta 42 levels than in Zbtb20^{Tg(PDGFB-APPSwInd)20Lms}/0 mice

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