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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		rnv7
retinal neovascularization 7
MGI:7716845
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		rnv7/rnv7 B6.Cg-rnv7/Boc MGI:7716856
hm2
 		rnv7/rnv7 STOCK-rnv7/Boc MGI:7716854


Genotype
MGI:7716856
hm1
Allelic
Composition		 rnv7/rnv7
Genetic
Background		 B6.Cg-rnv7/Boc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
rnv7 mutation (2 available); any rnv7 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
retina neovascularization ( J:353654 )
• Background Sensitivity: When assessed at 4 weeks of age, the phenotype on this C57BL/6J congenic background is less severe, with only 2-5 retinal spots on average, compared with homozygotes on a mixed background consisting predominantly of C57BL/6JEiJ and C3H/HeSnJ, where 5 to 7 retinal spots are seen on average

vision/eye
retina neovascularization ( J:353654 )
• Background Sensitivity: When assessed at 4 weeks of age, the phenotype on this C57BL/6J congenic background is less severe, with only 2-5 retinal spots on average, compared with homozygotes on a mixed background consisting predominantly of C57BL/6JEiJ and C3H/HeSnJ, where 5 to 7 retinal spots are seen on average




Genotype
MGI:7716854
hm2
Allelic
Composition		 rnv7/rnv7
Genetic
Background		 STOCK-rnv7/Boc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
rnv7 mutation (2 available); any rnv7 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

rnv7/rnv7 mice exhibit retina neovascularization.

cardiovascular system
retina neovascularization ( J:353654 )
• Background Sensitivity: When assessed at 4 weeks of age, the phenotype on this background, consisting predominantly of C57BL/6JEiJ and C3H/HeSnJ is more pronounced, with 5 to 7 retinal spots on average, relative to only 2-5 retinal spots on average on a C57BL/6J congenic background.

vision/eye
retina neovascularization ( J:353654 )
• Background Sensitivity: When assessed at 4 weeks of age, the phenotype on this background, consisting predominantly of C57BL/6JEiJ and C3H/HeSnJ is more pronounced, with 5 to 7 retinal spots on average, relative to only 2-5 retinal spots on average on a C57BL/6J congenic background.




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory