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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		rnv8
retinal neovascularization 8
MGI:7730770
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		rnv8/rnv8 B6.Cg-rnv8/BocJ MGI:7730853


Genotype
MGI:7730853
hm1
Allelic
Composition		 rnv8/rnv8
Genetic
Background		 B6.Cg-rnv8/BocJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
rnv8 mutation (1 available); any rnv8 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

rnv8/rnv8 mice show retinal neovascularization at 4 weeks of age.

cardiovascular system
choroidal neovascularization ( J:354131 )
• choroidal neovascularization with leakage was found by fluorescein angiography
retina neovascularization ( J:354131 )
• retinal neovascularization found by approximately 3 weeks of age with scattered depigmented spots of the retina, which develop into large depigmented areas by 16 weeks of age and newly formed vessels were found in the retina at both time points.

vision/eye
choroidal neovascularization ( J:354131 )
• choroidal neovascularization with leakage was found by fluorescein angiography
retina neovascularization ( J:354131 )
• retinal neovascularization found by approximately 3 weeks of age with scattered depigmented spots of the retina, which develop into large depigmented areas by 16 weeks of age and newly formed vessels were found in the retina at both time points.




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory