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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Snip1em1Yiji
endonuclease-mediated mutation 1, Yichang Jia
MGI:7738204
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Snip1em1Yiji/Snip1em1Yiji C57BL/6J-Snip1em1Yiji MGI:7738301
ht2
Snip1em1Yiji/Snip1+ C57BL/6J-Snip1em1Yiji MGI:7738300
cx3
Rnu2-8nmf291/Rnu2-8nmf291
Snip1em1Yiji/Snip1+
involves: 129S4/SvJae * C57BL/6J MGI:7738298


Genotype
MGI:7738301
hm1
Allelic
Composition
Snip1em1Yiji/Snip1em1Yiji
Genetic
Background
C57BL/6J-Snip1em1Yiji
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Snip1em1Yiji mutation (0 available); any Snip1 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• no homozygotes are obtained




Genotype
MGI:7738300
ht2
Allelic
Composition
Snip1em1Yiji/Snip1+
Genetic
Background
C57BL/6J-Snip1em1Yiji
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Snip1em1Yiji mutation (0 available); any Snip1 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• mice do not exhibit neuron loss in the cerebellum




Genotype
MGI:7738298
cx3
Allelic
Composition
Rnu2-8nmf291/Rnu2-8nmf291
Snip1em1Yiji/Snip1+
Genetic
Background
involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rnu2-8nmf291 mutation (1 available); any Rnu2-8 mutation (1 available)
Snip1em1Yiji mutation (0 available); any Snip1 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice exhibit rescue of the ataxia seen in Rnu2-8nmf291/nmf291 homozygotes

mortality/aging
• mice exhibit extended life span compared to Rnu2-8nmf291/nmf291 homozygotes

nervous system
• mice exhibit partial rescue of the neuron loss seen in Rnu2-8nmf291/nmf291 homozygous cerebellum





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory