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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mtv8em1Tvg
endonuclease-mediated mutation 1, Tatyana Golovkina
MGI:7738705
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mtv8em1Tvg/Mtv8em1Tvg C57BL/6J-Mtv8em1Tvg MGI:7764723


Genotype
MGI:7764723
hm1
Allelic
Composition		 Mtv8em1Tvg/Mtv8em1Tvg
Genetic
Background		 C57BL/6J-Mtv8em1Tvg
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:346992 )
N
• splenic B cells isolated from 10.5-week-old females show no significant differences in Igh, Igk, and Igl gene segment usage relative to wild-type controls, indicating that the Ig repertoire is not altered
• although Mtv8 is an endogenous retrovirus mapped within the Igk locus, it has no effect on Igk recombination




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory