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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Exd2em1Rspi
endonuclease-mediated mutation 1, Ramesh S Pillai
MGI:7738844
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Exd2em1Rspi/Exd2em1Rspi involves: C57BL/6 MGI:7764712


Genotype
MGI:7764712
hm1
Allelic
Composition
Exd2em1Rspi/Exd2em1Rspi
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Exd2em1Rspi mutation (0 available); any Exd2 mutation (27 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• adult (>P60) male mice are overtly normal and exhibit normal testicular size and fertility
• despite misregulation of PIWI-interacting RNAs (piRNA) levels originating from specific pachytene piRNA clusters, the overall piRNA biogenesis is unaffected





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory