Phenotypes associated with this allele

• Allele Symbol: opr2
• Allele Name: optic ring 2
• Allele ID: MGI:7779612
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	opr2/opr2	B6.CALB-opr2/BocJ	MGI:7779652
hm2	opr2/opr2	CALB/RkJ	MGI:7779653

Genotype
MGI:7779652

hm1

• Allelic Composition: opr2/opr2
• Genetic Background: B6.CALB-opr2/BocJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal optic nerve morphology ( J:358068 )

• Background Sensitivity: optic ring and optic cupping found at 4 weeks of age, with the penetrance greater on CALB/RkJ than the C57BL/6J congenic

optic nerve cupping ( J:358068 )

vision/eye

abnormal posterior eye segment morphology ( J:358068 )

abnormal optic nerve morphology ( J:358068 )

• Background Sensitivity: optic ring and optic cupping found at 4 weeks of age, with the penetrance greater on CALB/RkJ than the C57BL/6J congenic

optic nerve cupping ( J:358068 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
coloboma		DOID:12270	OMIM:120200 OMIM:120300 OMIM:216820	J:358068

Genotype
MGI:7779653

hm2

• Allelic Composition: opr2/opr2
• Genetic Background: CALB/RkJ

nervous system

abnormal optic nerve morphology ( J:358068 )

• Background Sensitivity: optic ring and optic cupping found at 4 weeks of age, with the penetrance greater on CALB/RkJ than the C57BL/6J congenic

optic nerve cupping ( J:358068 )

vision/eye

abnormal posterior eye segment morphology ( J:358068 )

abnormal optic nerve morphology ( J:358068 )

• Background Sensitivity: optic ring and optic cupping found at 4 weeks of age, with the penetrance greater on CALB/RkJ than the C57BL/6J congenic

optic nerve cupping ( J:358068 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
coloboma		DOID:12270	OMIM:120200 OMIM:120300 OMIM:216820	J:358068