Phenotypes associated with this allele

• Allele Symbol: Vaultrc5^em1.1Vdgl
• Allele Name: endonuclease-mediated mutation 1.1, Joana A Vidigal
• Allele ID: MGI:7786417
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vaultrc5^em1.1Vdgl/Vaultrc5^em1.1Vdgl	involves: C57BL/6J * C57BL/6NCr * FVB/N	MGI:7786419

Genotype
MGI:7786419

hm1

• Allelic Composition: Vaultrc5^em1.1Vdgl/Vaultrc5^em1.1Vdgl
• Genetic Background: involves: C57BL/6J * C57BL/6NCr * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

decreased hematocrit ( J:359009 )

• hematocrit values, the percentage of red blood cells in the blood, are slightly reduced

• however, mice are recovered at the expected ratio at weaning and mice are histologically normal, with normal weight, neural tissue (cortex, medulla, hippocampus, brain stem, corpus callosum, and cerebellum), liver, lung, heart, kidney, spleen, intestine, pancreas, ovaries and testis, and bone and normal white and red blood cell counts, red blood cell size, and hemoglobin levels

abnormal platelet cell number ( J:359009 )

• platelet counts are reduced to about 78% of the wild-type values, however platelet values remain well within the normal physiological ranges