Phenotypes associated with this allele

• Allele Symbol: Rr504^em4Takas
• Allele Name: endonuclease-mediated mutation 4, Shuji Takada
• Allele ID: MGI:7787033
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr504^em4Takas/Rr504^em4Takas	C57BL/6J-Rr504^em4Takas	MGI:7787122
ht2	Rr504^em1Takas/Rr504^em4Takas	involves: C57BL/6 * C57BL/6J * DBA/2	MGI:7787129

Genotype
MGI:7787122

hm1

• Allelic Composition: Rr504^em4Takas/Rr504^em4Takas
• Genetic Background: C57BL/6J-Rr504^em4Takas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

oligozoospermia ( J:334329 )

♂ • spermatogenesis in center seminiferous tubules, but aspermatic seminiferous tubules at poles

digestive/alimentary system

abnormal anogenital distance ( J:334329 )

♂ • reduced anogenital distance/body weight (AGD/BW) ratio

embryo

embryo phenotype ( J:334329 )

N • mice born at normal Mendelian ratios

endocrine/exocrine glands

decreased testis weight ( J:334329 )

♂ • reduced testis weight/body weight ratio

reproductive system

oligozoospermia ( J:334329 )

♂ • spermatogenesis in center seminiferous tubules, but aspermatic seminiferous tubules at poles

abnormal anogenital distance ( J:334329 )

♂ • reduced anogenital distance/body weight (AGD/BW) ratio

decreased testis weight ( J:334329 )

♂ • reduced testis weight/body weight ratio

Genotype
MGI:7787129

ht2

• Allelic Composition: Rr504^em1Takas/Rr504^em4Takas
• Genetic Background: involves: C57BL/6 * C57BL/6J * DBA/2

reproductive system

secondary sex reversal ( J:334329 )

♂ • external female genitalia and internal female gonads