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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Qrfprem1Smln
endonuclease-mediated mutation 1, Simon M Luckman
MGI:7788184
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Qrfprem1Smln/Qrfprem1Smln C57BL/6NTac-Qrfprem1Smln MGI:7788259


Genotype
MGI:7788259
hm1
Allelic
Composition
Qrfprem1Smln/Qrfprem1Smln
Genetic
Background
C57BL/6NTac-Qrfprem1Smln
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Qrfprem1Smln mutation (0 available); any Qrfpr mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
N
• mice exhibit no body weight phenotype on either normal chow diet or high-energy diet, normal spontaneous 24-hour and fast-induced re-feeding, no obvious differences in food intake or glucose handling, no evidence of abnormal bone development, and no differences in locomotor activity during both daytime and night-time phases
• intracerebroventricular administration of a 43-amino acid RFamide, pyroglutamylated arginine-phenylamine-amide peptide (QRFP) does not increase food intake or activity as seen in wild-type mice





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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory