Phenotypes associated with this allele

• Allele Symbol: Qrfprl^tm1.1Smln
• Allele Name: targeted mutation 1.1, Simon M Luckman
• Allele ID: MGI:7788186
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Orfprl^tm1.1Smln/Orfprl^tm1.1Smln	involves: C57BL/6NTac	MGI:7788260

Genotype
MGI:7788260

hm1

• Allelic Composition: Orfprl^tm1.1Smln/Orfprl^tm1.1Smln
• Genetic Background: involves: C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:355747 )

N • mice exhibit no body weight phenotype on either normal chow diet or high-energy diet, normal spontaneous 24-hour and fast-induced re-feeding, no obvious differences in food intake or glucose handling, no evidence of abnormal bone development, and no differences in locomotor activity during both daytime and night-time phases

abnormal response/metabolism to endogenous compounds ( J:355747 )

• intracerebroventricular administration of a 43-amino acid RFamide, pyroglutamylated arginine-phenylamine-amide peptide (QRFP) does not increase food intake or activity as seen in wild-type mice