Phenotypes associated with this allele

• Allele Symbol: Smndc1^em1Rkbr
• Allele Name: endonuclease-mediated mutation 1, Robert K Bradley
• Allele ID: MGI:7788963
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Smndc1^em1Rkbr/Smndc1^em1Rkbr	B6(Cg)-Smndc1^em1Rkbr	MGI:7788972

Genotype
MGI:7788972

hm1

• Allelic Composition: Smndc1^em1Rkbr/Smndc1^em1Rkbr
• Genetic Background: B6(Cg)-Smndc1^em1Rkbr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:353843 )

• both male and female offspring from homozygous breedings are smaller during early postnatal development

• however, homozygous offspring from heterozygous matings show normal body size at weaning

decreased body weight ( J:353843 )

• female offspring from homozygous breedings show a 14.1%, 20.52%, and 13.79% weight reduction at postnatal weeks 2, 3, and 4, respectively; the weight reduction persists until postnatal week 6

• male offspring from homozygous breedings show a 13.01% and 10.68% weight reduction at postnatal weeks 3 and 4, respectively

• female pups show greater weight reduction and for greater duration that male pups