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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zfp574m1Btlr
mutation 1, Bruce Beutler
MGI:7790451
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Zfp574m1Btlr/Zfp574m1Btlr C57BL/6J-Zfp574m1Btlr MGI:7790488


Genotype
MGI:7790488
hm1
Allelic
Composition		 Zfp574m1Btlr/Zfp574m1Btlr
Genetic
Background		 C57BL/6J-Zfp574m1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfp574m1Btlr mutation (0 available); any Zfp574 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased B cell number ( J:354285 )
• low percentage of B cells in the peripheral blood
abnormal T cell physiology ( J:354285 )
• diminished T cell-dependent antibody responses to recombinant Semliki Forest virus-encoded Beta-galactosidase
abnormal humoral immune response ( J:354285 )
• diminished T cell-dependent antibody responses to recombinant Semliki Forest virus-encoded Beta-galactosidase

hematopoietic system
decreased B cell number ( J:354285 )
• low percentage of B cells in the peripheral blood
abnormal T cell physiology ( J:354285 )
• diminished T cell-dependent antibody responses to recombinant Semliki Forest virus-encoded Beta-galactosidase




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory