All Phenotypes Rtf2<tm1c(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rtf2^{tm1c(KOMP)Wtsi}
targeted mutation 1c, Wellcome Trust Sanger Institute
MGI:7852632

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Rtf2^{tm1c(KOMP)Wtsi}/Rtf2^{tm1d(KOMP)Wtsi}	involves: C57BL/6 * C57BL/6N * FVB/N * SJL	MGI:7852646

Allelic Composition	Rtf2^{tm1c(KOMP)Wtsi}/Rtf2^{tm1d(KOMP)Wtsi}
Genetic Background	involves: C57BL/6 * C57BL/6N * FVB/N * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtf2^{tm1c(KOMP)Wtsi} mutation (0 available); any Rtf2 mutation (17 available)
Rtf2^{tm1d(KOMP)Wtsi} mutation (0 available); any Rtf2 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

decreased fibroblast proliferation ( J:360903 )

• slow proliferation of primary MEFs following cre treatment with few cells in S phase

decreased DNA replication ( J:360903 )

• decrease in replication speed and shortening of the inter-origin distance in cre-treated MEFs

homeostasis/metabolism

decreased DNA replication ( J:360903 )

• decrease in replication speed and shortening of the inter-origin distance in cre-treated MEFs

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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