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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Map4em2Coop
endonuclease-mediated mutation 2, Thomas A Cooper
MGI:7865836
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Map4em2Coop/Map4em2Coop FVB/NJ-Map4em2Coop MGI:7865852


Genotype
MGI:7865852
hm1
Allelic
Composition		 Map4em2Coop/Map4em2Coop
Genetic
Background		 FVB/NJ-Map4em2Coop
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map4em2Coop mutation (0 available); any Map4 mutation (230 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
decreased grip strength ( J:358165 )
• significantly decreased in males at 10 weeks of age
• trending toward decreased but not significantly different in females

muscle
muscle phenotype ( J:358165 )
• no signs of muscle cell loss or atrophy in the gastrocnemius muscles




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory