Phenotypes Associated with This Genotype

Genotype
MGI:2174712

• Allelic Composition: Prnp^tm1Rcm/Prnp^tm1Rcm
• Genetic Background: 129P2/OlaHsd-Prnp^tm1Rcm

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal susceptibility to prion infection ( J:45908 )

• altered incubation time following infection with transmissible spongiform encephalopathy

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	Creutzfeldt-Jakob disease	DOID:11949	OMIM:123400	J:45908
NOT	fatal familial insomnia	DOID:0050433	OMIM:600072	J:45908
NOT	Gerstmann-Straussler-Scheinker syndrome	DOID:4249	OMIM:137440	J:45908