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Phenotypes Associated with This Genotype
Genotype
MGI:2174792
Allelic
Composition		 Ttpatm1Far/Ttpa+
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ttpatm1Far mutation (1 available); any Ttpa mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal vitamin E level ( J:66419 )
• chow-fed heterozygotes exhibit a ~50% reduction of alpha-tocopherol levels in plasma and most tissues

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
familial isolated deficiency of vitamin E DOID:0090028 OMIM:277460
 J:66419

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory