Phenotypes Associated with This Genotype

Genotype
MGI:2174969

• Allelic Composition: Mapt^tm1Noh/Mapt^tm1Noh
• Genetic Background: involves: 129S4/SvJae

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal axon morphology ( J:19030 )

• abnormal cerebellar parallel fiber axons; reduction in microtubule (MT) number and density and reduction in frequency of cross-bridges between MTs

• mice exhibit no other obvious abnormalities

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	Alzheimer's disease	DOID:10652		J:19030