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Phenotypes Associated with This Genotype
Genotype
MGI:2175186
Allelic
Composition		 Ntrk1tm1Par/Ntrk1tm1Par
Genetic
Background		 involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntrk1tm1Par mutation (0 available); any Ntrk1 mutation (62 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased sensory neuron number ( J:60927 )
• reduction in sensory neuron number by E13
small dorsal root ganglion ( J:60927 )
• 84% reduction of dorsal root ganglion neurons at P0

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
hereditary sensory neuropathy DOID:0050548 OMIM:PS162400
 J:60927

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory