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Phenotypes Associated with This Genotype
Genotype
MGI:2175803
Allelic
Composition
Crybb2Aey2/Crybb2+
Genetic
Background
C3HeB/FeJ-Crybb2Aey2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crybb2Aey2 mutation (1 available); any Crybb2 mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• dark particles present in the anterior suture
• dark bodies and dustlike particles noted in the subcortical zone
• swollen and liquefied fibers noted in the anterior suture
• displayed as early as eye opening (day 12) as a diffuse opacity in the cortex and abnormally branched anterior suture
• total opacity develops after 8 to 11 weeks of age

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
cataract 3 multiple types DOID:0110269 OMIM:601547
J:70508


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory