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Phenotypes Associated with This Genotype
Genotype
MGI:2176950
Allelic
Composition
Gcktm1Ts/Gck+
Genetic
Background
either: (involves: 129S7/SvEvBrd * C57BL/6J) or (involves: 129S7/SvEvBrd * DBA/2J)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gcktm1Ts mutation (1 available); any Gck mutation (63 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• hyperglycemia in fed and fasted states; normal insulin levels observed
• decreased glucose tolerance shown in glucose tolerance tests

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
maturity-onset diabetes of the young type 2 DOID:0111100 OMIM:125851
J:29255


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory