Phenotypes Associated with This Genotype

Genotype
MGI:2177042

• Allelic Composition: Twist1^Pde/Twist1^Pde
• Genetic Background: involves: 129S1/Sv * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:69450 )

• animals resorbed by E11

nervous system

open neural tube ( J:69450 )

• failure of neural tube closure

exencephaly ( J:69450 )

embryo

open neural tube ( J:69450 )

• failure of neural tube closure

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Saethre-Chotzen syndrome		DOID:14768	OMIM:101400 OMIM:180750	J:69450