Analysis Tools
mortality/aging
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• Background Sensitivity: no live born hemizygotes, unlike in crosses to C57BL/6 or outbred Swiss mice
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• despite normal numbers at E9.5, fewer than expected mice at E15.5 and weaning
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cardiovascular system
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• in some mice
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• interruption in some mice
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• in 4 of 18 mice at E9.5
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• sinisteral looping in some mice
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• in some mice
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dextrocardia
(
J:192577
)
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• in some mice
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• in some mice
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craniofacial
cleft palate
(
J:192577
)
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• in 5 of 58 mice at E15.5
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digestive/alimentary system
cleft palate
(
J:192577
)
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• in 5 of 58 mice at E15.5
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• midline and right-sided stomach in some mice
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• in some mice
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embryo
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• cells appear larger
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• in 12 of 18 mice
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• in 5 of 58 mice at E15.5
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• the teardrop structure at the distal tip of the embryo is irregular and forms non-cohesive groups of node cells
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• shorter
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growth/size/body
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• in 12 of 18 mice
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• in some mice at E9.5
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cleft palate
(
J:192577
)
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• in 5 of 58 mice at E15.5
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heterotaxia
(
J:192577
)
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• laterality defects in 3 of 15 mice
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• in some mice
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• in some mice
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• in some mice
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nervous system
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• in 5 of 58 mice at E15.5
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exencephaly
(
J:192577
)
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• in 5 of 58 mice at E15.5
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respiratory system
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• in some mice
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cellular
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• shorter
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| visceral heterotaxy | DOID:0050545 |
OMIM:306955 OMIM:605376 OMIM:606325 OMIM:613751 OMIM:614779 OMIM:PS306955 |
J:75951 | |
